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The shocking murders that shook New York City in 2024Beloved McDonald's wraps to return in 2025, company president confirmsDENVER — As part of a national “moonshot” to cure blindness, researchers at the University of Colorado Anschutz Medical Campus will receive as much as $46 million in federal funding over the next five years to pursue a first-of-its-kind full eye transplantation. “What was once a dream — to cure blindness — is potentially within our grasp,” the campus’ chancellor, Don Elliman, said during a press conference Monday morning. The University of Colorado team, led by researcher Dr. Kia Washington, was one of four in the United States that received funding awards from the federal Advanced Research Projects Agency for Health , or ARPA-H. The CU-based group will focus on achieving the first-ever vision-restoring eye transplant by using “novel stem cell and bioelectronic technologies,” according to a news release announcing the funding. Researchers have already successfully completed the transplant procedure — albeit without vision restoration — in rats. Now they’re set to proceed to larger animals, Washington said. A team at New York University performed a full eye transplant on a human patient in November 2023, though the procedure — while successful — did not restore the patient’s vision. Washington said developing a small-animal model, even without vision restoration, was a key milestone in advancing the project. The goal is to fully restore the optic nerve — which carries visual information from the eye to the brain — and to fully connect a patient’s brain with a donor’s eye. The CU team will work on large animals next to advance “optic nerve regenerative strategies,” the school said, as well as to study immunosuppression, which is critical to ensuring that patients’ immune systems don’t reject a donated organ. The goal is to eventually advance to human trials. ARPH-A, created two years ago, will oversee the teams’ work in the coming years. Researchers at 52 institutions nationwide will contribute to the teams. The CU-led group will include researchers from the University of Southern California, the University of Wisconsin, Indiana University and Johns Hopkins University, as well as from the National Eye Institute . The total funding available for the teams is $125 million, ARPA-H officials said Monday. The money is provided in a contract, not a grant, and ARPA-H officials likened it to a venture capital approach: The four teams will compete alongside each other, and projects showing success or promise will receive full funding over the next five years. The teams may also be combined or lean on each other, depending on their results, Washington said in an interview. The project is ambitious, officials said. But its success could unlock deeper medical advancements. “If you can do this, just think about what you could do for traumatic brain injury, for spinal cord injury,” said ARPA-H’s Dr. Calvin Roberts, an ophthalmologist who will oversee the broader project. “And so those of us who work in the eye, what we love about working in the eye is that it’s just a model for things that are going around elsewhere in the body.” The other teams’ research will include “3-D printed click-lock gel technology with micro-tunneled scaffolds containing stem cell-derived retinal cells,” donor eye procurement and the actual performing of transplant surgeries, according to ARPA-H. The effort to cure blindness, Washington joked, was “biblical” in its enormity — a reference to the Bible story in which Jesus cures a blind man. She and others also likened it to a moonshot, meaning the effort to successfully put Neil Armstrong and Buzz Aldrin on the moon nearly 50 years ago. If curing blindness is similar to landing on the moon, then the space shuttle has already left the launchpad, Washington said. “We have launched,” she said, “and we are on our trajectory.” ©2024 MediaNews Group, Inc. Visit at denverpost.com . Distributed by Tribune Content Agency, LLC.

NoneHansi Flick lamented another "really bad" performance as were held to a 2-2 draw at on Saturday, dropping points for the fourth time in five LaLiga games. Barça twice led through and but a penalty and a 94th minute goal from earned Betis a share of the spoils at the Benito Villamarín. The league leaders have now lost two, drawn two and won just one of their last five fixtures, which has seen their advantage over second place , who still have a game in hand after beating Girona later on Saturday, cut from nine points to two. "It was not a good match," Flick said in the post-game news conference. "We have a young team and we have to improve a lot. It's what we have to do. It's up to us, we have the quality to win every match but we also have to show that." Flick's second half substitutions were also questioned after the game. With the match evenly balanced, he replaced the team's top scorers Lewandowski and in addition to midfielders and . The German coach admitted he did so with one eye on the midweek Champions League trip to , although he also pointed out Barça had struggled with them on the pitch, too. "I know that, but at first we played really bad, also from the beginning," he responded when asked about his changes. "The first situation we played good [in the game] was the Lewandowski goal [in the 39th minute]. "I think we became better also in second half [with the changes]. Of course we had to bring new legs, fresh legs, and we tried for that. We have on Wednesday a big match in the Champions League. We also have to take care about that." Lewandowski's opener was cancelled out when substitute brought down , on loan at Betis from Barça, in the box, with Lo Celso dispatching the subsequent penalty. The spot kick was only given after a lengthy VAR review, though, which angered Flick and led to him being sent off "coming out of his technical area, shouting, gesticulating and protesting a decision," according to the referee's report. "I said nothing to anyone," Flick insisted. "It was just a reaction from myself. I have to accept it. I don't want to speak about referees. I never do this. "I think this was a reaction because it took a long time to look if it was a penalty or not. If it's like this, I'm not sure if it's clear. "I'm really disappointed about [my red card]. I thought that would never happen to me. But here, maybe it's like that, and I have to accept it." Flick said Barça would not appeal the dismissal -- or the touchline ban which will follow -- and praised his assistant Marcus Sorg for his management of the latter stages of the encounter. Barça thought they had won it after Flick's dismissal when Yamal brilliantly set up Torres with his ninth assist of the season -- a league high - in the 82nd minute, but Diao's stoppage time strike earned a point for the home side.

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